Adobe have announced that Reader will run in a sandbox called Protected Mode blogs.adobe.com/asset/2010/07/%20introducing-adobe-reader-protected-mode.html. It is based on Microsoft's  Practical Windows Sandboxing blogs.msdn.com/b/david_leblanc/archive/2007/07.aspx. This is good news as it will drastically reduce the attack surface of Adobe Reader and mitigate the impact of any vulnerabilities within the product.

Cheers,
Adrien de Beaupré
Intru-shun.ca Inc.